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March 6, 2025
This video, developed by Prof. Efrat Dotan and Prof. Shubham Pant, discusses the diagnosis and management of metastatic pancreatic ductal adenocarcinoma (PDAC), a lethal disease which is usually diagnosed at an advanced stage and has an extremely poor diagnosis.

Topics covered in this video include:
• The most reported symptoms
• Different risk factors and main diagnostic tools
• Overview of treatments available
• Considerations for treatment selection
• Targeted therapy

Download the slides and summary flashcard and access the accredited e-learning here: https://cor2ed.com/gi-connect/programmes/metastatic-pancreatic-ductal-adenocarcinoma-pdac/?media=0

Key clinical takeaways:
• Pancreatic ductal adenocarcinoma (PDAC) is usually diagnosed at an advanced, incurable stage due to non-specific symptoms and has an extremely poor prognosis
• Recognition of symptoms and known risk factors is important for an early diagnosis
• Systemic chemotherapy is the standard treatment for mPDAC but molecularly targeted treatments and immunotherapies may have a role for specific patients
• Choice of treatment depends on several factors, including patients' performance status and co-morbidities
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