American Neurological Association

As the global burden of neurological disorders continues to grow, a diverse community of physician-scientists are pushing the limits of neuroscience research to combat disease and bring novel treatments to people worldwide. The ANA is the professional ally of physicians and researchers who strive to make a difference through careers that combine neurological discovery, education, and clinical care.

From advances in stroke and dementia to movement disorders and epilepsy, members of the American Neurological Association are at the forefront of research and practice devoted to understanding neurological health and treating diseases of the nervous system. As the premier professional society of academic neurologists and neuroscientists since 1875, the ANA continues to set the standard for research and practice through its popular Annual Meeting, the highly ranked journals Annals of Neurology and Annals of Clinical and Translational Neurology (ACTN), and through advocacy for national policies that serve the best interest of researchers, practitioners, and patients.


 

Compartmentalized Inflammation as a Target for Remyelination in Multiple Sclerosis

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October 4, 2024

Compartmentalized Inflammation as a Target for Remyelination in MS brought to you from the American Neurological Association’s 149th Annual Meeting featuring Jennifer Orthmann-Murphy, MD, PhD.

In multiple sclerosis, the peripheral immune system targets and damages myelin, oligodendrocytes and axons. Within the central nervous system compartment, microglia, astrocytes and oligodendrocyte precursor cells react to demyelination and axonal damage, and their reactive responses influence the ability to repair and replace lost myelin. The mechanisms that underly these reactive responses offer novel therapeutic targets for progressive multiple sclerosis biology. 

To see more cutting-edge research presented at the ANA2024 meeting, please navigate to https://education.myana.org/ 

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